10 Risk factors for Cardiovascular Disease
The American College of cardiology has classified the risk factors into many categories based on the researches done.
1) Cigarette Smoking :
- Smoking is synergistic with other risk factors and directly influences acute coronary events including thrombus formation & plaque instability.
- Risk also increases with increase in number of smokes per day.
- Nicotine and by-products of smoking are involved in the initiation and progression of atherosclerosis(Plaque Formation).
- Smoking reduces HDL (good cholesterol) and increases VLDL cholesterol(Bad cholesterol) and glucosse levels.
- Quitting smoking can reduce the CVD risk by 50%
2) LDL Cholesterol :
- A decrease of 1 mg/dl of LDL-C results in 1-2% decrease in the relative risk or CVD.
- Following factors increase LDL-C :
- Aging
- Genetics
- Diet
- Diabetes
- Some anti-Hypertensive drugs
- Obesity
- Reduced estrogen levels
- Diets high in saturated fat and cholesterol elevate LDL-C.
- < 100 mg/dl : Optimal Level
- 100-129 mg/dl - Near Optimal
- 130-159 mg/dl - Borderline high
- 160-189 mg/dl - High
- >190 mg/dl - Very High
3) Hypertension :
- About 50% of the first Myocardial infarction patients & 66% of the stroke patients have blood pressure higher than 160/90 mm Hg.
- Hypertension is normally present with other risk factors.
4) Diabetes.
5) Physical Inactivity :
- 30 min of moderate activity of moderate intensity is recommended.
5) HDL-Cholesterol :
- An increase in HDl-C has a direct correlation with a decreased CVD risk.
- A low HDL-C (<40 mg/dl) iis considered to be risk factor.
6) Obesity :
- Android type(Apple shaped body type) of obesity is more prone to increase the risk to CVD as compared to the gynoid (Pear shaped body type) type.
7) Trans-Fat :
- They are produced in the hydrogenation process.
- Widely used in the food industry to manufacture hydrogenated fats and soft margarine.
- 50% of the trans-fatty acid intake comes from animal foods e.g. beef. butter, milk fats.
- Remaining 50% comes from hydrogenated oil.
- Other major sources are margarine. commercial frying fat, high fat baking goods, shortening.
8) Carbohydrate(CHO) intake :
- Restriction of sugar may lower the serum triglyceride levels.
- A vegetarian diet which in high in complex CHO is emphasized : make use of legumes, unrefined cereals, fruits & vegetables.
- These have a hypo-cholesterlemic effect.
9) Age :
- Incidence of pre- mature disease in men, 35-44 years of age is 3 times as high as the incidence in women of the same age.
- Thus, men above 45 years and women after 55 years are at an increased risk for CVD.
10) Family History :
- A family history of pre-mature disease is a strong risk factor even when other factors are considered.
- Numerous hyperlipidemias are inherited and lead to pemature CVD.
- If none of the parents have CVD, the % of the child getting CVD is 8%
- If 1 parent has CVD, the % of the child getting CVD is 16%
- If both have CVD, the % of the child getting CVD is 32%